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Citalopram – drugs that is prescribed by a specialist (usually a psychiatrist) for depressive episodes of moderate and severe, and panic disorders.

Citalopram: General information

The action of citalopram online is typically made through an intermediary deceleration reuptake transmission of nerve impulses in the central nervous system (CNS) such as serotonin. As a result, the concentration of released serotonin in nerve synapses increases, which in most cases are associated with improved mood, the normalization of behavior, relieved the state of physical, mental and emotional areas that are disturbed in depression and panic disorders.

Citalopram: Indications

If you are going to take citalopram, read the following indications of use.

Citalopram selectively acts on serotonin reuptake, and no other possible neurotransmitters in the central nervous system, so it belongs to the group of selective serotonin reuptake inhibitors (SSRIs), which confirms the high clinical efficacy of the drug (at therapeutic concentrations of citalopram) with a minimum of side effects, if compare it with the older generation antidepressants : monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants.

It should be noted that citalopram has different from other SSRIs chemical structures (isobenzofuran bicyclic derivative), unparalleled among other antidepressants, and accordingly has some differences in the mechanism of antidepressant action, showing the effectiveness where other drugs may be ineffective.

Citalopram has no effect on the serum levels of prolactin and growth hormone. Citalopram does not impair cognitive / intellectual function and psychomotor performance and has no sedative effect. Citalopram has no severe toxicity to heart, but caution is needed when high doses of Citalopram (40 mg daily), or if both are assigned with citalopram other drugs, particularly those that affect the increase in QT interval on the electrocardiogram. Before the appointment of the drug, please refer to the instructions for medical use.

Citalopram: Dosage

Citalopram is taken once a day, the course of treatment is long; the antidepressant effect usually develops after 2-4 weeks of treatment.

Citalopram belongs to a new generation of antidepressants with good tolerability, low toxicity and high safety in case of overdose.

The symptomatology that may occur at a sharp cancellation of Citalopram is not specific. Most often includes dizziness, headache, paresthesia, sleep disturbance, fatigue, nervousness, tremor, nausea and / or vomiting.

In the case when the course of treatment comes to end, it should be cancelled gradually over several weeks to avoid the syndrome of “cancellation.” In most cases this will be enough for about 2 weeks, but in each case the doctor decides that question individually : some patients may need a period of 2-3 months or more.

Citalopram: Side effects

As in the case of the use of other drugs of SSRI group, undesired side reactions are sometimes observed, but they are transient and mild.

Side effects of citalopram are observed within the first one or two weeks of treatment and usually substantially diminish with improvement of the patients’ condition.

You might order citalopram online or by visiting pharmacy.

The frequency of side effects : Very common – > 10%, and often – > 1% but < 10 %, rarely - > 0,1%, and < 1%, rarely - > 0,01%, but < 0.1 % ; very rare - < 0.01%.

If you are going to take the full course of treatment with citalopram, there might appear the following side effects.

Allergic reactions: rarely - increased sensitivity; very rare - anaphylactic reaction.

The central nervous system: very often - drowsiness, headache, tremors, dizziness, and often - migraine, paresthesia, sleep disorder, rarely - extrapyramidal disorder, seizures, rarely - serotonin syndrome (a combination of excitement, tremor, myoclonus and hyperthermia), the frequency of unknown - psychomotor agitation, akathisia.

Psychic sphere : very often - agitation, nervousness, and often - decreased libido, impaired orgasm ( for women), anxiety, confusion, drowsiness, impaired concentration, bizarre dreams, amnesia, rarely - aggression, depersonalization, hallucinations, delusions, euphoria, increased libido, frequency unknown - panic attacks, bruxism, suicidal thoughts.

From the digestive system: very often - dry mouth, nausea, constipation, and often - vomiting, flatulence, diarrhea, abdominal pain, hepatitis, the frequency is unknown - gastro -intestinal bleeding.

The cardiovascular system: very often - palpitations, and often - tachycardia, hypertension, orthostatic hypotension, rarely - bradycardia, decreased blood pressure, arrhythmia frequency is unknown - lengthening of the QT interval on the electrocardiogram.